The Journal of Bone and Joint Surgery (American), 91(), 955–960 (2009), DOI:10.2106/JBJS.H.00212
Malignant transformation of fibrous dysplasia into sarcoma is a rare event, occurring in less than 1% of cases1,2. Malignant transformation of fibrous dysplasia can also occur as part of Mazabraud syndrome, a syndrome characterized by fibrous dysplasia and intramuscular myxomas1. However, Mazabraud syndrome is so rare that only four cases of sarcomatous degeneration have been reported in the literature1,3-5. Here we report a fifth case, which involved the development of osteosarcoma in a fibrous dysplastic lesion of the proximal part of the radius in a patient with Mazabraud syndrome.
The patient was informed that data concerning the case would be submitted for publication, and he consented.back