The Journal of Pediatrics, 153(2), 287–289 (2008), DOI:10.1016/j.jpeds.2008.02.045
We observed increased bleeding tendency and platelet function abnormalities in 3 boys with McCune-Albright syndrome (MAS). We speculate that platelet dysfunction contributed to excessive blood loss in our patients. This report of platelet dysfunction in MAS highlights the need for assessment of platelet functions in the condition.
Abbreviations: ADP, Adenosine diphosphate; AMP, Adenosine monophosphate; MAS, McCune-Albright syndrome; PFA, Platelet function analyzer; PHP I, Pseudohypoparathyroidism I